Abstract： Objective: To explore the efficacy of deanxit combined with omeprazole and mosapride in treatment of elderly patients with gastroesophageal reflux disease. Methods:A total of 129 elderly patients with gastroesophageal reflux disease in our hospital,were randomly assigned to omeprazole,mosapride combined with deanxit(n=70) or omeprazole plus mosapride(n=59). the clinical efficacy and reflux, heartburn symptom score of the two groups were evaluated. Results: The total effective rate was higner in omeprazole,mosapride combined with deanxit (94.28%) than in omeprazole plus mosapride (61.02%). Reflux and heartburn and other symptoms in two groups were improved, and reflux symptoms score was significantly lower in omeprazole,mosapride combined with deanxit than in omeprazole plus mosapride(P< 0.05); Conclusion: improvement effect on reflux, heartburn and other symptoms is better in omeprazole,mosapride combined with deanxit than in omeprazole plus mosapride in senile patients with gastroesophageal reflux disease, and worthy of clinical application.
2013, Vol. 11 
