Abstract: Objective: To evaluate rational use of prescriptions of Chinese traditional patent medicine. Methods: 71040 prescriptions of Chinese traditional patent medicine at west-clinic in our hospital From May 2012 to April 2013 was checked by window pharmacist, and then the information on the connection letters about irrational prescriptions was statistical y analyzed; Besides responsible pharmacists randomly selected and evaluated prescriptions every month. Results: The rate of successful y interfering irrational prescriptions was 99%, the reasons for irrational prescriptions were the lost of signature or stamp, missing or lacking diagnosis, inappropriate dose, inappropriate way of taking medicine, irrational combination and overdose medication, furthermore, the rate of irrational prescriptions declined from 6.56% in June 2012 to 0.97% in April 2013. Conclusion: The work of Checking and evaluating prescriptions improve the level of rational use of Chinese traditional patent medicine, meanwhile, perfect cooperation of pharmacist, physician and department of administrating medicine was the key to get work better and better.