Abstract：Objective: To investigate the clinical characteristics and effect of antiplatelet drugs therapy on single lacunar infarction.in middle cerebral artery. Methods: A total of 60 patients with single lacunar infarction in middle cerebral artery within 72 hours occurred between January 2014 and October 2015 in Department of Neurology in Haidian Hospital of Beijing.We classified the patients into two groups according to leison location: single lacunar infarction with MCA disease group and single lacunar infarction without MCA disease group.We compared the two groups of patients with cerebral vascular disease risk factors (gender, age, hypertension, blood pressure variability, diabetes, coronary heart disease, stroke, smoking) and clinical characteristics (NIHSS and mRS, white matter). Results: There were statistical difference in hypertension, diabetes, coronary heart disease, stroke, smoking, blood pressure variability, NIHSS and mRS,white matter signal (P <0.05) between the two groups. Conclusion: The difference in clinical characteristics, etiology and pathogenesis in patients with single lacunar infarction with MCA disease suggest the diversity of MCA perforating single lacunar infarction. So it isnecessary to take different measures to treat.
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2016, Vol. 14 
