Abstract：Objective: The characteristics of adverse drug reactions (ADRs) induced by carbapenems in our hospital were analyzed to provide reference for the clinical application of carbapenems. Methods: 52 ADRs induced by carbapenems were collected from 2005 to 2015 in our hospital. These ADRs were analyzed in respects of gender, age, primary disease, drug, injury of organ/system, clinical manifestation and clinical prognosis. Results: There are 37 males (71.15%) and 15 females (28.85%) in 52 patients. People aged from 18 to 60 have the highest risk of ADR. The primary disease in 52 patients are respiratory diseases, injuries of skeletons and muscles and multiple organ dysfunction. In respect of injury of organ/system, majorities are nervous system, skin and its appendages. 77.55% patients recovered completely after drug withdrawal. Conclusion: In order to reduce the risk of ADR induced by carbapenem, Monitoring should be implement when carbapenem is administered in clinic. Rational use of carbapenems should be strengthened.
2016, Vol. 14 
