Pharmaceutical care on the elderly patients of pemetrexed combined with carboplatin with non-small cell lung cancer
YANG Jun, CHEN Zhe, HE Fei, ZHU Zhi-xiang, ZHOU Hai-yan, LI Guo-hui*
Department of Pharmacy, National Cancer centre/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100021, China
Abstract:Objective: To probe into the operation and management of pharmaceutical care on the elderly patients with non-small cell lung cancer. Methods: By adjusting the chemotherapy drug dosage and analgesia drug, combined with the clinical guidelines, clinical pharmacist can summarize the main points of pharmaceutical care of elderly patient with NSCLC. Results: The elderly patients of have better clinical tolerance with carboplatin, and should be monitored the renal function because of the nephrotoxicity of platinum and renal excretion of pemetrexed; pharmacist can adjust the dose of chemotherapy combination drugs (anticoagulant, lipid-lowering drug, analgesia) in order to improve patients’ compliance with chemotherapy, and reduce the adverse drug reaction. Conclusion: With the pharmacists’ participating in clinical chemotherapy of elderly NSCLC patients, it was to formulate individualized dosage regimen, and improve the patient's medication compliance and quality of life.
杨珺,陈喆,贺飞,朱志祥,周海燕,李国辉. 1 例培美曲塞联合卡铂治疗老年非小细胞肺癌患者的药学监护[J]. 临床药物治疗杂志, 2017, 15(3): 52-55.
YANG Jun, CHEN Zhe, HE Fei, ZHU Zhi-xiang, ZHOU Hai-yan, LI Guo-hui. Pharmaceutical care on the elderly patients of pemetrexed combined with carboplatin with non-small cell lung cancer. CLINICAL MEDICATION JOURNAL, 2017, 15(3): 52-55.
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