骨科术后感染危险因素及抗感染治疗方案探讨

doi:10.3969/j.issn.1672-3384.2015.02.013

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摘要目的：调查分析骨科术后感染的危险因素，总结骨科术后感染的抗感染治疗方案及转归，为今后预防治疗术后感染提供参考。方法：回顾性分析于2013 年1月-2014 年4 月本院骨科术后感染41 例患者。结果：患者伤口感染发生率1.05%，年龄、体重指数（BMI）、个人史（吸烟、饮酒）、糖尿病史以及住院情况、手术情况（时长、输血、失血、植入物等）对手术感染均有影响。抗感染治疗药物主要包括万古霉素、哌拉西林钠- 他唑巴坦钠（特治星）、头孢哌酮钠舒巴坦钠（舒普深）和左氧氟沙星等。结论：术后感染与患者个人基本情况，长时间住院及术中污染情况有关，应予足够重视并采取有效措施预防感染；另外，抗感染治疗方案的合理性有待改进。

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	刘莹
	崔向丽
	刘丽宏

关键词 ：骨科术后感染, 危险因素, 抗感染, 合理用药

Abstract：Objective: To analyze and investigate the risk factors of orthopedic postoperative infection, summarize the anti-infection treatment and its therapeutic effect, and provide prevention and interventions for infection in the future. Methods: 41 cases of postoperative infection from January 2013 to April 2014 in our hospital were retrospectively analyzed. Results: Totalled wound infection rate was 1.05%,the patient's age, body mass index (BMI), personal history (smoking, drinking), diabetes history, hospitalization, surgery conditions (duration,blood transfusion, blood loss, implants, etc) influenced postoperative infections. Anti-infection drugs included Vancomycin, Piperacillintazobactam,Cefoperazone Sodium, Sulbactam Sodium and levofloxacin etc. conclusion: Postoperative infection was concerned with individual factors, long hospitalization duration and intraoperative pollution ,which should be highly considered with further effective prevention measures. The rationality of the anti-infection treatment needs to be imp roved.

Key words： orthopedic postoperative infection risk factors anti-infectio n rational drug use

收稿日期: 2014-12-05

:	R978
	R687

通讯作者: 崔向丽，刘丽宏 E-mail: cui10@163.com;hongllh@yahoo.com.cn

引用本文:

刘莹，崔向丽，刘丽宏. 骨科术后感染危险因素及抗感染治疗方案探讨[J]. 临床药物治疗杂志, 2015, 13(2): 53-58.
LIU Ying, CUI Xiang-li, LIU Li-hong. Orthopaedic postoperative infection risk factor and anti-infection treatment. CLINICAL MEDICATION JOURNAL, 2015, 13(2): 53-58.

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