Abstract：A 82-year old male patient was admitted into our hospital and he had no blood system disease, and the blood platelet was in the normal range on admission. After giving nadroparin for 2 days, imipenem and cilastatin sodium for 6 days, his platelet count reduced to 66×109?L-1 and nadroparin was withdrawn. Imipenem and cilastatin sodium was switched to ceftazidime. On admission day 13,his platelet count reduced to 36×109?L-1, ceftazidime and ambroxol hydrochloride injection were discontinued and the patient was given Leucogen 40mg TID treatment to raise the platelet while his platelet count still decline sharply. On the 20th day of admission, his platelet count reduced to 20×109?L-1 and montelukast was discontinued. On 24th day of admission, his platelet count recovered to 57×109?L-1, and the patient condition was generally good with no special discomfort, normal temperature and urine volume, then the patient was discharged.
郑芸颖, 崔向丽, 刘丽宏. 药物引发血小板严重减少症1 例[J]. 临床药物治疗杂志, 2017, 15(3): 64-66.
ZHENG Yun-ying, CUI Xiang-li, LIU Li-hong. A case of drug-induced severe thrombocytopenia. CLINICAL MEDICATION JOURNAL, 2017, 15(3): 64-66.
2017, Vol. 15 
