Abstract：A 77-year-old female patient with rheumatoid arthritis (RA) was seen because of fever, dyspnea, cough, purulent sputum and interstitial lung changes. LEF (20 mg/day) combined with MTX(12.5mg/week) began before 5 months. The withdrawal of LEF and MTX was on the iffth day after the fever, the chest CT revealed ground glass shadowing and consolidations forming a mosaic pattern in lung ifelds;bronchi alveolar lavage (BAL) cel:total was 0.49×106/ml, macrophages 58.50%, lymphocytes 41.50%, neutrophils 0.00%, eosinophils 0.00%, PCP negative. Pneumonia, Interstitial Pneumonia (drug-induced ) were diagnosed. The patient underwent oxygen therapy , anti-infection , anti-inlfammatory , diuretics , spasmolysis, with low salt and fat diet. The patient's temperature returned to normal after a three days of steroid hormones, the lung lesion was signiifcantly improved on chest X-ray and CT 10 days later, and also pleural effusion was reduced on ultrasonic testing.
2013, Vol. 11 
